Ototropin 10 i.u./10 vials– HGH is a hormone that is normally produced by the body. It really is synthesised and secreted by skin cells in the anterior pituitary gland located at the base of the mind. HGH stimulates many metabolic processes in cells. HGH affects protein, fat, carbohydrate and mineral metabolism. The major role of HGH is to stimulate the liver to secrete Insulin-like Growth Factor-I (IGF-I). IGF-I stimulates production of cartilage cells, resulting in bone growth and also plays a key ro
…Ototropin 10 i.u./10 vials
|Contents||Vial: HGH (191aa Human Growth Hormone) lyophilised powder 10iu.
Ampoule: 2ml Sterile water for injection.
|Administration||Intramuscular or Subcutaneous injection.|
|Ototropin 10 i.u./10 vials Storage||Store at room temperature away from heat and direct sunlight pre reconstitution. Refrigerate between 2-8’C post Reconstitution.|
|Dosage||Adult: SC Growth hormone deficiency Initial: 6 mcg/kg/day. May increase dose gradually. Max: 12.5 mcg/kg/day. HIV-associated wasting or cachexia 0.1 mg/kg/day at bedtime. May take on alternate days for patients at increased risk of adverse effects. Max: 6 mg/day. Short bowel syndrome100 mcg/kg/day for 4 wk. Max: 8 mg/day.|
|Contraindications||Acute critical illness due to heart or abdominal surgery, multiple accidental trauma or respiratory failure; active neoplasms, proliferative or preproliferative diabetic retinopathy; lactation; patients with closed epiphyses. Intracranial lesions. Patients with Prader-Willi syndrome who are severely obese or have severe respiratory impairment.|
|Special Precautions||Monitor thyroid function; benign intracranial hypertension. DM; may require dose reduction in insulin. Pregnancy. Discontinue treatment if there is evidence of tumour growth. Monitoring in patients with scoliosis is recommended due to risk of progression of scoliosis.|
|Adverse Drug Reactions||Hypothyroidism, peripheral oedema; headache; muscle and joint pain; benign intracranial hypertension. Loss of glycaemic control in diabetics.|
|Ototropin 10 i.u./10 vials.Drug Interactions||High doses of corticosteroid may inhibit growth-promoting effects of somatropin.|
|Pregnancy Category (US FDA)||Category B: Either animal-reproduction studies have not demonstrated a foetal risk but there are no controlled studies in pregnant women or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the 1sttrimester (and there is no evidence of a risk in later trimesters).|
|ATC Classification||H01AC01 – somatropin ;|